- Substituted vinylcephalosporins
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β-Lactam compounds of the formula STR1 wherein R5 represent cyclopropyl or methyl, useful as antibiotics.
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- 3-(substituted)propenyl-7-(aminothiazolylacetamido) ceph-3-em-4-carboxylic acids and esters thereof
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This invention provides novel cephalosporanic acids and esters thereof having the general formula STR1 wherein R2 is hydrogen, or lower acyl, R3 is hydrogen, or lower alkanoyloxy, and R4 is hydrogen, 5-methyl-2-oxo-1,3-dio
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- 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
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This invention provides novel cephalosporanic acids and esters thereof having the general formula STR1 wherein R2 is hydrogen, lower alkyl, lower alkenyl, lower alkynyl, cyclo(lower)alkyl or acyl, R3 is hydrogen, lower alkyl, lower a
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- 7-amino-3-propenylcephalosporanic acid and esters thereof
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This invention provides novel cephalosporin intermediates, 7β-amino-3-[(Z)-1-propen-1-y1]-3-cephem-4-carboxylic acid and esters thereof having the general formula STR1 wherein the configuration of the 3-propenyl group is Z sometimes referred to as cis- and R is hydrogen or a conventional carboxy-protected group, or a physiologically hydrolyzable esterifying group, and acid addition salts thereof and the metal salts of the foregoing substance wherein R is hydrogen. These compounds are useful as intermediates for preparation of orally active cephalosporins.
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