Synthesis and biological evaluation of a series of novel inhibitor of Nek2/Hec1 analogues
High expression in cancer 1 (Hec1) is an oncogene overly expressed in many human cancers. Small molecule inhibitor of Nek2/Hec1 (INH) targeting the Hec1 and its regulator, Nek2, in the mitotic pathway, was identified to inactivate Hec1/Nek2 function media
Qui, Xiao-Long,Li, Guideng,Wu, Guikai,Zhu, Jiewen,Zhou, Longen,Chen, Phang-Lang,Chamberlin, A. Richard,Lee, Wen-Hwa
experimental part
p. 1757 - 1767
(2010/02/28)
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